Ship of Theseus
Biotechnology developing degradation-resistant Hox transcription factors for the diseases of aging
Ship of Theseus is developing a fleet of biologics based on the homeobox (HOX) family of transcription factors. The 39 HOX genes are master regulators of many context-specific cell phenotypes and coordinated tissue-level behaviors.
The 39 Homeobox genes can be thought of as a piano with 39 keys. By playing different chords (different combinations of HOXs), almost any cell behavior can be generated.
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Details last updated 08-Mar-2025