Stem cells take aim at Alzheimer’s: A first-in-human regenerative trial
Drug Target Review - 26-Aug-2025Early trial shows patient gains after Wnt-activated stem cells injected directly into the brain
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Clinical-stage biotech company based in Newport Beach, California
Regeneration Biomedical is a clinical-stage biotech company based in Newport Beach, California, founded by neurosurgeon Dr. Christopher Duma. The company is pioneering a first-of-its-kind stem cell therapy for neurodegenerative diseases—such as Alzheimer’s, Parkinson’s, ALS, MS, stroke, and traumatic brain injury—by harvesting a patient’s own fat-derived stem cells, activating them with Wnt signaling, and delivering them directly into the brain’s ventricular system. This innovative method bypasses the blood–brain barrier, aims to stimulate regenerative repair, reduce inflammation, and has entered Phase 1 clinical trials evaluating safety and early efficacy.
Visit website: https://regenerationbiomedical.com/
Details last updated 28-Aug-2025
Early trial shows patient gains after Wnt-activated stem cells injected directly into the brain