Dr. Julian Sale is a Programme Leader at the MRC Laboratory of Molecular Biology in Cambridge and Associate Faculty at the Wellcome Sanger Institute, where his research explores how cells replicate DNA when faced with damage or structural obstacles. His work focuses on translesion synthesis, a pathway that enables DNA replication to continue past lesions but can also introduce mutations linked to cancer and other diseases. Using a blend of cell genetics, biochemistry, imaging, and biophysical tools, his lab investigates how proteins coordinate at stalled replication forks and how these processes influence genome stability, evolution, and cellular function. Sale also holds roles as Francis Crick Lecturer, Fellow at Gonville & Caius College, and Senior Executive Editor of Nucleic Acids Research.