Catriona Jamieson, M.D., Ph.D., holds several leadership roles at UC San Diego — she is a Professor of Medicine, Deputy Director at the Moores Cancer Center, Chief of the Division of Regenerative Medicine, Director of the Sanford Stem Cell Institute, and Co-Leader of the Hematologic Malignancies Program. Her lab studies blood-forming stem and progenitor cells in conditions called myeloproliferative neoplasms (MPNs), which are disorders where the body makes too many blood cells and can lead to clots or evolve into acute leukemia. She focuses in particular on the mutant stem cells that evade chemotherapy, lie dormant, and later reactivate — driving disease relapse or resistance. Her goal is to develop therapies that are more selective and less toxic, targeting these rogue stem cells to improve outcomes for patients with blood cancers.