Alastair is a Cancer Research UK Clinician Scientist and spends 50% of his time in research at Nuffield Department of Surgical Sciences, University of Oxford. 

His research goal is to provide a robust molecular platform for accurate decision-making in early stage prostate cancer. He has spent his scientific training investigating how individual genes or groups of genes have driven prostate cancer behaviour. His PhD thesis investigated the role of HES6 as a transcriptional driver in castrate resistant prostate cancer – he found that this single gene fundamentally changed the nature of prostate cancer cells. Since then, he has been employing integrative genomics in prostate cancer risk stratification as well as disease modelling with patient derived xenografts.