Space travel harms muscles but young cells fight back with stimulation
Live Forever Club - 04-Jul-2025This insight may help astronauts and older adults maintain muscle health
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Drug discovery pharmacologist
Dr. Siobhan Malany is a drug discovery pharmacologist. She is an associate professor in Cellular and Systems Pharmacology at the University of Florida. She leads in-space research using tissue-chip technology to study human muscle biology in microgravity. Since 2014, she has sent five payloads to the ISS.
In August 2024, she won the ISS National Lab’s Compelling Results Award for her muscle-aging study in space. Her work uses patient-derived 3D muscle tissue chips inside automated cube-labs on the ISS. The goal is to understand aging better and create treatments for age-related muscle loss.
She holds a Ph.D. in organic chemistry from the University of Iowa and completed a postdoc in pharmacology at UC San Diego. She founded Micro-gRx in 2015 to develop lab-on-chip systems. She also directs Florida’s In-Space Biomanufacturing Human Health Innovation Hub and C-STARS center.
Her lab focuses on age-related muscle wasting (sarcopenia), receptor pharmacology, and small-molecule drug discovery. She collaborates with Mayo Clinic on molecules targeting cardiovascular receptors.
Visit website: https://pharmacy.ufl.edu/profile/malany-siobhan/
See alsoDetails last updated 04-Jul-2025
This insight may help astronauts and older adults maintain muscle health