Dr. Denis Evseenko is the Founding Director of the USC PARRIS Longevity Accelerator and is the Vice Chair for Research in Orthopaedic Surgery as well as a Professor of Orthopaedic Surgery and Stem Cell Biology & Regenerative Medicine at the Keck School of Medicine of USC. Renowned as a global leader in understanding immune stressors and their critical role in diseases, Dr. Evseenko has spearheaded groundbreaking research on how chronic inflammation contributes to age-related conditions. Under his leadership, the Accelerator builds on his pioneering work developing first-in-class therapies that target systemic inflammation and tissue degeneration, effectively bridging fundamental scientific discoveries with clinical applications. Notable innovations from his lab include R805/CX-011, a novel small-molecule therapy currently advancing toward human clinical trials, and Plurocart, a stem cell-based implant designed to regenerate cartilage. ​With over $30 million secured in competitive research funding and his election as a Senior Member of the National Academy of Inventors, Dr. Evseenko is widely recognized for his ability to translate cutting-edge research into transformative treatments.