Debut is a San Diego–based, vertically integrated biotech beauty company that blends advanced AI, genomics, and sustainable biomanufacturing to create novel, high-performing skincare ingredients. Through its pharmaceutical-grade AI platform, BeautyORB, which can screen over 50 billion molecules and predict their effects on 30,000 human genes, Debut rapidly discovers new bioactives tied to skin health claims like anti-inflammaging, barrier repair, and cellular longevity. These AI-identified ingredients undergo rigorous validation—RNA sequencing, functional assays, safety testing—before being produced sustainably via microbial fermentation and enzyme-driven processes. Debut also offers formulation services through BiotechXBeautyLabs, enabling brands to access custom and white-label biotech-powered products with clinically backed and eco-friendly credentials.