Want to live forever? Join the club!
Join the growing number of people who are committed to living forever. Now that healthcare has merged with IT the exponential growth in medical technology means immortality may be closer than you think. From drug research and diagnostics to exoskeletons and nanobots – rapid advances are increasing our life expectancy every day.
Radical life extension is a growing industry – and more and more people are putting (a lot!) of money where their mouths are:
- 5 billionaires who want to live forever – Fortune Magazine
- Understanding Calico: Larry Page, Google Ventures, and the quest for immortality – The Verge
- Oracle founder Larry Ellison has proclaimed his wish to live forever and donated more than $430 million to anti-aging research. – Washington Post
Healthy Lifestyle May Increase Lifespan by 7 Years – Medspace – 20-Jul-2017
People who never smoked cigarettes, were not obese and drank alcohol in moderation had life expectancy of 87 years instead of 80.
Few studies look at the effect of multiple health behaviours.
Quitting smoking, even late in life, increases longevity.
Study from nearly 15,000 Americans aged 50 to 89 years.
Meet the film-maker with the camera eye – BBC News – 20-Jul-17
Rob Spence is blind in one eye.
Nine years ago he replaced his eye with a tiny video camera.
It’s not connected to his optic nerve but sends its footage to a receiver.
Inspired by his bionic man toy!
Brain implant turns ‘loser’ mice into aggressive fighters – Ars Technica – 18-Jul-2017
In tube test the mice who shoves the most wins the dominance game.
Scientists used optogenetics to trigger the dmPFC region of a low-ranking mouse’s brain.
The dorsomedial prefrontal cortex is associated with “effortful behavior” and “social dominance.”
Stimulated low ranking mice won almost every contest.
In some mice the winner effect continued after light stimulation stopped.
Rises in UK life expectancy levelling off – BBC News – 18-Jul-2017
Life expectancy has been rising for decades, but has recently slowed.
We were living an extra 2-3 months for every year passed.
‘Entirely possible’ austerity is affecting how long people live.
Other countries, such as Hong Kong, continue to see consistent rises.
COMMENT: looking at the graph its about to go negative this year
When your body becomes eligible for an upgrade – BBC News – 15-Jul-2017
What will happen when humans decide to become robots?
Sensors give prosthetic legs an awareness of what is around them.
Rich and fortunate may become physically superior, too.
Redesigning how limbs are amputated to create the right mechanical and electrical interfacing environment that would join the brain directly to the limb.
3D-printed silicone heart beats like the real thing – Engadget – 14-Jul-2017
Single solid silicone structure using a 3D-printing, lost-wax casting technique.
Doesn’t have the usual disadvantages of metallic and plastic mechanisms.
Designed to imitate the human heart as closely as possible in form and function.
Unfortunately currently only lasts for 3,000 beats – about 45 minutes.
Scan finds heart’s ticking time bombs – BBC News – 13-Jul-2017
Inflammation is linked to the build-up of unstable plaques in blood vessels.
This inflammation changes the behaviour of fat around the outside of blood vessels.
CT scans can be use to analyse the fat and inflammation around arteries.
Hoping technology could predict heart attacks in people who appear healthy.
Compound in Strawberries Slows Aging in Mice – LEAF Science – 13-Jul-2017
Fisetin is a naturally occurring plant polyphenol from the flavonoid group.
It is found in many fruits and vegetables, such as strawberries, apples, persimmons, onions, and cucumbers.
Found to clear senescent cells in a petri dish.
No evidence that fisetin has a senolytic effect in mice in vivo.
When added to the diet of SAMP8 mice delays some of the accelerated aging.
New method to accurately determine functional age of cells – News Medical – 11-Jul-17
Considers biophysical qualities of cells, such as cell movements and structural features.
Other methods work at DNA or tissue level.
Examined dermal cells taken from people between the ages of 2 to 96.
Could help evaluate health effects and improve other treatments.
Coffee drinkers live longer – perhaps – BBC News – 11-Jul-2017
Drinking three cups of coffee a day may help you live longer.
Study of almost half a million people from 10 European countries.
Effect seen even if it is decaffeinated.
Particularly linked to a lower risk of heart and gut diseases.
An extra cup of coffee could extend life by 1 or 3 months for women and men respectively.
Robots Will Soon Replace Doctors In Healthcare – Forbes – 10-Jul-2017
Current surgical robots make ths job easier for a human surgeon.
Next generation of personal healthcare robots will make use AI to act as your domestic nurse.
Reminding patients about medication, coaching them through their chronic illness and communicating with healthcare professionals.
Luxury apocalypse-safe bunkers – Independent – 10-Jul-2017
Able to withstand everything from extreme weather like tornadoes, to a full blown nuclear attack.
Luxury apartments were originally missile silos.
Survival Condo selling them for $1.5m to $4m.
COMMENT: one day I hope to offer the same for the not-so-rich, but maybe without the cinema and kids waterslide!
Frequent ejaculation may decrease prostate cancer risk – NHS – 6-Jul-2017
Men who ejaculate more than 20 times a month less likely to report prostate cancer than those ejaculating less than 8 times per month.
26% reduction in risk of prostate cancer for men aged over 50.
Study does not prove cause – only that it is associated with a reduction in risk.
May help reduce stress or keep cell metabolism well regulated.
Cohort study following up male health professionals from 1992 for 18 years.
Cancer vaccines could eliminate tumours – New Scientist – 5-Jul-2017
Researchers have been trying to find ways to ramp up the immune response to tumours.
Two new techniques involve making a personalised vaccine that targets many of a person’s cancer molecules at once.
Tumours did not occur in two thirds of people with skin cancer in trial.
A new breed of scientist, with brains of silicon – Science Mag – 05-Jul-2017
Robots use sound waves to create droplets a thousand times smaller than one a human can transfer.
But they also plan the experiments – interpreting data and generating hypotheses.
Zymergen tunes industrial microbes that produce ingredients for biofuels, plastics, or drugs.
This is already a $160-billion-per-year sector.
Can run a thousand experiments per week compared to a typical human’s 10 per month.
400-year-old sharks could hold the secret to long life – Inews – 5-Jul-2017
Greenland sharks are the longest living vertebrate on the planet.
Arctic University of Norway have sequenced the whole nuclear genome of almost 100 sharks.
DNA obtained from tiny clippings from sharks which are caught on a line and released.
Treating Diabetes by Altering Other Cells to Produce Insulin – LEAF Science – 4-Jul-2017
Novel approach seeks to cure type 1 diabetes and to allow type 2 diabetics to stop using insulin shots
Researchers able to increase the types of pancreatic cells that secrete insulin.
New therapy uses gene transfer to introduce new genes into cells in the pancreas.
Mice cured for one year without any side effects.
Clinical trials in the next three years.
Heartburn drugs linked to premature death – NHS – 4-Jul-2017
PPIs reduce the amount of acid in the stomach.
Used to treat heartburn and people at risk of stomach ulcers (e.g. if taking low-dose aspirin).
Cohort study of over 300,000 US veterans shows an association – not cause.
Not seen in people taking H2 blockers like ranitidine (Zantac).
Every cancer patient could have DNA tested – Independent – 4-Jul-2017
Professor Dame Sally Davies envisions millions of patients having their DNA tested routinely.
Whole genome sequencing involves 3.2 billion letters of code.
Price of tests has to an average £680.
60 % of cancer patients have actionable data – mutations that can shape future treatment.
Cruise ship air quality worse than polluted cities – Independent – 4-Jul-2017
Each day a cruise ship emits as much particulate matter as a million cars.
Air on the deck downwind of the ship’s funnels had 84,000 ultra-fine particulates per cubic centimetre.
Figure for London’s Piccadilly Circus was only 38,400.
Short term exposure can cause increasing respiratory symptoms.
Stormram 4 – smallest MRI-compatible 3D printed biopsy robot – 3ders – 30-Jun-2017
Poised to have a major impact on diagnosis and treatment of breast cancer.
Manual breast biopsies can be a difficult procedure.
Previous robotic solutions limited due to the strong magnetic field of MRA scanners.
Stormram 4 is 3D printed entirely from plastic and runs on air pressure instead of electricity.
No Known Limit To How Long Humans Can Live – Time – 28-Jun-2017
Paper in last year’s Nature human body and brain petered out around 115.
Now five critiques highlight assumptions that weren’t warranted.
Maximum lifespan in a population varies year to year and can have a sudden drop when longest-lived human dies.
Stroke prevention device wins healthtech award – Pharmaphorum – 28-Jun-2017
Embotrap II is developed and marketed by Neuravi.
Small, mesh-like construct can restore blood flow through vessels by removing clots.
Designed to trap clot with minimal compression and rapidly deliver TICI 2b-3 reperfusion.
Now acquired by Codman Neuro, part of the Johnson & Johnson.