Want to live forever? Join the club!
Join the growing number of people who are committed to living forever. Now that healthcare has merged with IT the exponential growth in medical technology means immortality may be closer than you think. From drug research and diagnostics to exoskeletons and nanobots – rapid advances are increasing our life expectancy every day.
Radical life extension is a growing industry – and more and more people are putting (a lot!) of money where their mouths are:
- 5 billionaires who want to live forever – Fortune Magazine
- Understanding Calico: Larry Page, Google Ventures, and the quest for immortality – The Verge
- Oracle founder Larry Ellison has proclaimed his wish to live forever and donated more than $430 million to anti-aging research. – Washington Post
Racquet sports, swimming and aerobics tied to lower risk of early death – WebMD – 29-Nov-2016
People who played racquet sports had an almost 50 percent lower risk of dying from any cause during the 15-year study.
Swimming and aerobics each were associated with a nearly 30 percent lower risk of premature death from any cause.
No significant associations were found for participation in football and running.
Study included 80,000 adults with average age of 52 in England and Scotland.
Big data promise exponential change in healthcare – FT – 29-Nov-2016
GlaxoSmithKline employs online technology and a data algorithm developed by F1’s elite McLaren Applied Technologies team.
Potential lies in its ability to fine tune research and clinical trials.
Helped by continued falls in data storage costs and improving computing power.
Handling the personal details of millions of people creates huge data quality, privacy and security problems.
Data gathered 10 years ago by a brain scan is infinitely less detailed than what you would get today
DNA repair and metabolism as determinants of species longevity – eLife Sciences – 22-Nov-2016
Mammalian lifespan differs by >100-fold
Skin fibroblasts from 16 species of mammals studied under identical cell culture conditions.
Key features of cells from longer-lived species:
1. up-regulated genes involved in DNA repair and glucose metabolism
2. down-regulated proteolysis and protein transport
3. high levels of amino acids but low levels of lysophosphatidylcholine and lysophosphatidylethanolamine
First-time birth in later life may increase longevity – Medical News Today – 18-Nov-2016
Average age of American mothers has increased from 24.9 years in 2000 to 26.3 years in 2014.
First births in women aged 35 years and over also increased by 23 percent.
Older age in mothers has been linked to a variety of adverse birth outcomes, such as multiple births and congenital disabilities.
But mothers who had their first child when they were 25 years or older were more likely to survive to age 90.
Multiple pregnancies also increases chance of living to 90.
Personalised breast cancer programme launches in Cambridge – Drug Target Review – 18-Nov-2016
Cancer Research UK Cambridge Institute’s programme will map patients’ DNA and RNA to tailor treatment to individuals.
Will analyse the genome and all expressed genes of tumour cells from 250 breast cancer patients.
There are around 10 different types of breast cancer and these respond differently to the available treatments.
“We’re looking at ways to predict this response ensuring individual patients get the best treatment for them.” – Sir Harpal Kumar
Extend your healthspan by caring for yourself daily – The Daily Progress – 18-Nov-2016
Living long and living well are not the same.
It is both possible and common to outlive your health.
Average American will live through nine years of disease and disability.
If you commit to managing your condition and focus on regaining the greatest level of wellness available to you, you can extend your healthspan despite having a chronic condition.
Dreaded Superbug Has Officially Arrived in the United States – IEET – 17-Nov-2016
US Centers for Disease Control has identified over a dozen cases of antibiotic-resistant fungus, Candida auris.
Four of the first seven patients infected with it have died.
Typically treated with a class of antifungal drugs called echinocandins but some now found to be resistant to all three major classes of medications.
Patients probably acquired their infections locally.
Candida auris can spread quite easily with traces found on patient’s mattress, furniture and windowsill.
Eating a well aged cheese could help you live longer – Business Insider – 15-Nov-2016
Research published in Nature Medicine finds the compound spermidine improves cardiovascular health.
Spermidine found in many foods including aged cheese, legumes and whole grains.
Study of 800 Italians found that eating more spermidine foods was also associated with lowered blood pressures.
Previous studies have shown it extends the lifespans of simple organisms such as fruit flies and roundworms as well as mice.
Is staying single actually good for your health? – Yahoo News – 14-Nov-2016
Many studies have said that married people are the ones who live longer.
However, Bella DePaulo has authored Singled Out: How Singles Are Stereotyped, Stigmatized, and Ignored, and Still Live Happily Ever After.
Married people are more likely to agree with the statement, “I gave up trying to make big improvements in my life a long time ago.”
Single people who are self-sufficient are less likely to experience negative emotions and also exercise more.
First home brain implant lets locked-in woman communicate – New Scientist – 12-Nov-2016
Used at home in a person’s day-to-day life, without the need for doctors and engineers
58 years old woman was diagnosed with amyotrophic lateral sclerosis (ALS) in 2008.
Relies on an eye-tracking device to communicate – but doesn’t work well outdoors.
Existing implants tend to need recalibrating by a team of engineers on a daily basis.
University Medical Center Utrecht device has 2 electrodes that record brain activity and wirelessly sends a signal to an external computer tablet.
After 6 months training patient has 95% accuracy and takes 20 seconds to select a letter.
German Robot Controlled From Russia With an Exoskeleton (VIDEO) – Motherboard – 12-Nov-2016
German Research Centre for Artificial Intelligence (DFKI) designed AILA in 2010.
AILA has been adapted to be controlled by CAPIO, its new passive exoskeleton system.
CAPIO uses 8 different contact points on a complex exoskeleton to manipulate AILA in real time.
Series of advanced sensors in its hands allow it to feel its way around the environment.
COMMENT: A general purpose robot in the house that could be controlled by a doctor in a medical emergency
Sore throat sufferers urged to take pharmacy test – BBC – 12-Nov-2016
Sore Throat Test and Treat service will determine if an illness is caused by a virus or a bacterial infection.
Results from a throat swab, which measures sugars on the tongue, are provided in five minutes.
Walk-in service is aimed at reducing doctor appointments and to help reduce the over-use of antibiotics.
In a trial only 10% people were given a prescription – “a massive reduction.”
Community ‘Well-Being’ Helps You Live Longer – WebMD – 10-Nov-2016
People in more contented U.S. counties lived an extra two years or more.
Well-being includes physical health as well as people’s levels of emotional health, life satisfaction, optimism and security.
Direct correlation found between well-being and life expectancy regardless of the area’s racial makeup, poverty and education levels.
Efforts to improve Americans’ health and longevity have to go beyond the health care system.
First flu affects lifetime risk – BBC – 11-Nov-2016
Research finds there are only two types of hemagglutinin protein on surface of influenza A virus.
Chances of falling ill from a new strain of flu are at least partly determined by the first strain they ever encountered.
75% protection rate against severe disease if patient exposed to a virus with the same protein motif when they were a child.
The first time a person’s immune system encounters a flu virus, it makes antibodies targeting hemagglutinin .
Could explain why some flu outbreaks cause more deaths and serious illnesses in younger people.
Scouts and guides provide mental health boost for life – BBC – 10-Nov-2016
Study finds scouts or guides have better mental health in later life.
15% less likely than other adults to suffer anxiety or mood disorders at the age of 50.
Could be the lessons in resilience and resolve that such organisations offer that has a lasting positive impact.
Same benefit was not evident from other types of volunteering.
Data from a lifelong study of almost 10,000 people from across the UK who were born in November 1958
COMMENT: Particularly important as suicide is the leading cause of death of British men under 50 years of age.
World’s first light-seeking synthetic nanorobot – Indian Express – 9-Nov-2016
Same size as a blood cell potentially allowing them to be injected into a patient’s body.
Novel nanotree structure means the nanorobots respond to light shining on them like moths being drawn to flames.
Nanorobots are composed of two common and low-price semiconductor materials: silicon and titanium oxide.
Could help surgeons remove tumours and enable more precise engineering of targeted medications.
Oxford researchers developing a diabetes breathalyzer – MobiHealthNews – 9-Nov-2016
University of Oxford are developing a portable non-invasive device to detect diabetes and monitor glucose levels.
Work-in-progress published in the American Chemical Society’s journal Analytical Chemistry
Uses an absorbent polymer that traps acetone from exhaled breath and then probes with a laser to determine its concentration.
Previous studies studies have found that elevated levels of acetone are found in the exhaled breath of diabetes patients.
Accuracy of the device tested under a range of conditions, e.g. after exercising, fasting overnight.
How not exercising transforms your brain (VIDEO) – Business Insider – 7-Nov-2016
Study of athletes aged between 50-80 who ran an average of 36 miles per week.
Master athlete’s brains get significantly less blood flow after not exercising for 10 days
The hippocampus, which is responsible for building and storing memories, notably got less blood flow to it.
But no impact on cognition tests.
END OF DEATH says leading researcher – Express – 1-Nov-2016
Aubrey de Grey speaking at technological Inman Connect conference.
By your 20s the regeneration of cells is outpaced by the death of cells leading to ageing.
Molecular and cellular damage will one day be a thing of the past.
Will be tackled with regenerative medicines such as stem cell and gene therapies coupled with drugs and vaccinations.
Modern pharmaceutical industry focussing its efforts on delaying diseases, rather than beating them.
People who have stronger social networks live longer – Independent – 1-Nov-2016
People with stronger social networks and relationships tend to live longer – also true of the online world.
Online activity of the 12 million people over six months studied.
Facebook users 12 per cent less likely to die in any given year.
The bigger the social network the better.
Activity that indicates offline social interaction (e.g. posting photos) tended to live longest.