This episode of the LongeCity interviews podcast brings together two pioneers in rejuvenation research—Liz Parrish, founder of BioViva, and Bill Andrews, founder of Sierra Sciences. They share updates on groundbreaking gene therapies, ongoing advocacy efforts, and their vision for the future of life extension.

Key Points:

Liz Parrish and Bill Andrews discuss groundbreaking gene therapy innovations and their advocacy for accessible rejuvenation treatments. The episode highlights the future of life extension research and regulatory pathways to bring innovative therapies to patients.

• Gene Therapy Advancements: Liz Parrish discusses her personal experience with multiple gene therapies, including telomerase reverse transcriptase and myostatin blockers, designed to slow aging and promote systemic rejuvenation. She highlights the potential of redosing protocols to enhance therapy effectiveness over time.
• New Vectors in Research: BioViva has shifted its research focus to cytomegalovirus (CMV) vectors, which can carry larger genetic payloads than traditional adeno-associated virus (AAV) vectors. This change aims to improve gene delivery, reduce immune responses, and allow for more efficient redosing.
• Best Choice Medicine Initiative: A regulatory proposal co-developed by Liz Parrish and Bill Andrews, Best Choice Medicine offers terminally ill patients access to innovative, unapproved treatments. It provides a parallel path to FDA processes, focusing on safety and early access for those in critical need.
• Rally for Longevity Rights: Scheduled for spring 2026, this large-scale advocacy event aims to raise awareness about life extension treatments and push for regulatory changes. Both Liz and Bill will be key speakers at the rally, which seeks to unite stakeholders in the rejuvenation field.
• Personal Health Tips: Liz and Bill emphasize the importance of consistent exercise, maintaining a balanced diet tailored to individual sensitivities, and avoiding unhealthy fads. They advise consulting functional medicine experts and staying informed about the latest in health and longevity science.
• Future Outlook: Both speakers express optimism about the future of aging research, pointing to rapid advancements in gene therapy and the potential of regulatory reform. They see these developments as key to making life extension treatments accessible and impactful globally.