Wihuri Research Institute (WRI) is a non-profit biomedical research institute founded in 1944. The research program in the Wihuri Research Institute is focused on the vascular system in various diseases – such as cardiovascular and inflammatory diseases, and cancer. The mission of the Institute is to achieve new fundamental understanding of the molecular and cellular basis of the vascular system, in order to improve the treatment of various diseases. The Wihuri Research Institute is led by Academy professor Kari Alitalo.

The Wihuri Research Institute has become widely known in medical circles for its work on diseases of the heart and circulatory system. Contacts with researchers overseas are extensive.

The Institute is located in Biomedicum Helsinki, at the Meilahti Academic Medical Center, which comprises activities of the University of Helsinki and the University Helsinki Hospital. Research activities are linked within the campus and internationally connected, and the Institute benefits from shared technology core facilities at the campus.