A virtual cell lab: scientists build digital twin to simulate human biology
Johns Hopkins Medicine - 25-Jul-2025Digital cells forecast disease and drug response
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Assistant Professor in the Neuroscience Department at Johns Hopkins University School of Medicine
Genevieve Stein‑O’Brien, Ph.D., MHS, is an Assistant Professor in the Neuroscience Department at Johns Hopkins University School of Medicine and serves as the Assistant Director of the JHU Single Cell Consortium. She holds affiliations across multiple institutes, including the Brain Science Institute, Genomics Medicine, Oncology, and the Kavli Neuroscience Discovery Institute. Dr. Stein‑O’Brien leads a deeply interdisciplinary research program combining computation, statistics, and experimental biology to decipher the stochastic gene regulatory dynamics that underlie neurodevelopment and disease. Her lab develops transfer‑learning methods and mathematical models to integrate multi‑modal single‑cell data, enabling predictions of cell behaviour and variation across individuals, with applications in areas like ALS, FTD, aging, and cancer.
Visit website: https://neuroscience.jhu.edu/research/faculty/163
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See alsoDetails last updated 31-Jul-2025
Digital cells forecast disease and drug response