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Genevieve Stein-O’Brien

Assistant Professor in the Neuroscience Department at Johns Hopkins University School of Medicine

Genevieve Stein‑O’Brien, Ph.D., MHS, is an Assistant Professor in the Neuroscience Department at Johns Hopkins University School of Medicine and serves as the Assistant Director of the JHU Single Cell Consortium. She holds affiliations across multiple institutes, including the Brain Science Institute, Genomics Medicine, Oncology, and the Kavli Neuroscience Discovery Institute. Dr. Stein‑O’Brien leads a deeply interdisciplinary research program combining computation, statistics, and experimental biology to decipher the stochastic gene regulatory dynamics that underlie neurodevelopment and disease. Her lab develops transfer‑learning methods and mathematical models to integrate multi‑modal single‑cell data, enabling predictions of cell behaviour and variation across individuals, with applications in areas like ALS, FTD, aging, and cancer.

Visit website: https://neuroscience.jhu.edu/research/faculty/163

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See also

Johns Hopkins Medicine

Governing structure for Johns Hopkins University

Details last updated 31-Jul-2025

Genevieve Stein-O’Brien News

A virtual cell lab: scientists build digital twin to simulate human biology

A virtual cell lab: scientists build digital twin to simulate human biology

Johns Hopkins Medicine - 25-Jul-2025

Digital cells forecast disease and drug response