The Kaufman laboratory uses human pluripotent stem cells to understand the development of blood cells (both hematopoietic stem cells and functional lymphocytes: T cells and NK cells) and related mesodermal cell populations (including bone, endothelial and smooth muscle/vascular cells). The aim is to use human pluripotent stem cells as a resource to produce blood and immune cells for new clinical applications for treatment of relapsed/refractory cancers -- both hematologic malignancies and solid tumors.

Dr. Kaufman also provides clinical care for patients with hematological malignancies, with special interest in blood and marrow transplantation (BMT) and immune therapies.