A way to reprogram mature cells into totipotent stem cells

03-Sep-2019
KEY POINTS FROM ARTICLE:

Scientists treated mature cells with natural molecules found in the early mouse embryo.
After seven days, the researchers observed 5-30 floating self-assembled blastocyst-like structures in culture.
Group investigated how similar their blastocyst-like structures were to actual blastocysts.
Scientists observed similar patterns of gene expression but at lower-than-natural levels.
Findings are published in the journal Stem Cell Reports.
Research was led by Dr Cody Kime at RIKEN, Japan and scientists from the US.

Creating totipotent stem cells opens ways for revolutionary findings in regenerative medicine
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