A way to reprogram mature cells into totipotent stem cells
Scientists treated mature cells with natural molecules found in the early mouse embryo.
After seven days, the researchers observed 5-30 floating self-assembled blastocyst-like structures in culture.
Group investigated how similar their blastocyst-like structures were to actual blastocysts.
Scientists observed similar patterns of gene expression but at lower-than-natural levels.
Findings are published in the journal Stem Cell Reports.
Research was led by Dr Cody Kime at RIKEN, Japan and scientists from the US.