Reversing epigenetic changes rejuvenated mice with progeria
Reprogramming resets the epigenetic marks that turn genes on and off.
Changes in histones and methylation marks that accumulate in the cells with ageing are reset.
Possible to turn back ageing by reversing these epigenetic changes.
Succeeded in rejuvenating mice with progeria but has to test this on normal animal models.
The first human tests of these techniques are likely to happen in the next few years.
Research by Salk Institute for Biological Studies, published in the journal Cell.