Purging damaged brain stem cells can improve cognition in Alzheimer’s

23-May-2019
KEY POINTS FROM ARTICLE:

Removal of malfunctioning brain stem cells improves cognition in Alzheimer’s.
Oligodendrocyte progenitor cells stop dividing and malfunction due to amyloid plaques in Alzheimer’s.
These OPCs go rogue and damage surrounding neural tissue.
Mouse were treated with two drugs dasatinib and quercetin that reduce senescent cells.
Cognition improved in mice treated with the drug combination compared to the control groups.
Potential to develop anti-senescent treatment for dementia.
Research by University of Kentucky Alzheimer’s Disease Research Center published in Nature Neuroscience.

Promising results in genetically altered mice with Alzheimer’s traits
Read full article on National Institute on Aging website
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